| Original document(17 pages) 中文版 |
The invention discloses a 2, 4-disubstituted heterocycle parallel [4,5-e][1,2,4] thiadiazines derivant preparing method in the chemical technique domain, which comprises the following steps: dissolving heterocycle parallel [1,2,4] thiadiazines parent in dimethyl formamide; adding in sodium hydride; stiring under 10 deg.c to white sediment; filling in halocarbon R2X; stirring and reacting; adding halocarbon R1X in liquor; reacting at 25-60deg.c for 10-24 hours; reducing pressure and steaming dissolvant; rinshing leavings; recrystallizating by organic solvent. R1, R2 represents bromine benzyl, double-bromine-bromine-benzyl, meta- bromine-bromine-benzyl and so on. The invention simplifies the operation, which has high yield. |
Application Number
申请号 |
200610043834 |
Application Date
申请日 |
2006.04.20 |
| Title 名称 |
Process for preparing 2,4-disubstituted heterocyclo [4,5-e][1,2,4] thiadiazine derivatives
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Publication Number
公开号 |
1837216 |
Publication Date
公开日 |
2006.09.27 |
| Approval Pub. Date |
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Granted Pub. Date |
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| International Classification 分类号 |
C07D513/04,C07D515/04 |
Applicant(s) Name
申请人 |
Shandong University |
| Address 地址 |
250012 |
| Inventor(s) Name 发明人 |
Liu Xinyong, Xu Wenfang |
| Attorney & Agent 代理人 |
bao guangmeng |
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