Original document(9 pages)  中文版
    The invention relates to polypeptide organic compound elected from the a, b, c, d, e, f, g, h , the molecular weight are respectively 915.96, 963.06, 763.86, 963.15, 902.07, 1031.18, 987.13, 951.14; it and the resisting B blood group monoclonal antibody specificity can be combined ; the it is dissolved in the water and the amino acid are connected by the peptide bond. The polypeptide organic compound provided by the invention and the antigenic antibody specificity prestored in the human body can be combined to close down its function; so the hyperacute rejection because of the heterogeneity organ transplantation can be interdicted differential, the invention is idiosyncratic compared with the natural antibody of resisting a-Gal prestored in human body in the combining site, so it has the function of blocking antibody; at the same time, it dont affect the whole immunoreaction of the human body and can avoid the side effect induced by the usual immunosuppressant.
Application Number
申请号
200610050164 Application Date
申请日
2006.03.31
Title 名称 Polypeptide organic compounds and application in xenogeneic transplantation
Publication Number
公开号
1831003 Publication Date
公开日
2006.09.13
Approval Pub. Date Granted Pub. Date
International Classification 分类号 C07K7/06,A61K38/08,A61P41/00
Applicant(s) Name
申请人
Zhejiang Univ.
Address 地址 310027
Inventor(s) Name 发明人 Zhan Jinbiao, Lang Jianshe, Xu Linhai
Attorney & Agent 代理人 zhang fagao zhao hangli

  
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