| Original document(53 pages) 中文版 |
The present invention relates to new D3 and D2 dopamine receptor subtype preferring ligands of formula (I): wherein R1 and R2 represent independently a substituent selected from hydrogen, alkyl, aryl, cycloalkyl, aroyl, or R1 and R2 may form a heterocyclic ring with the adjacent nitrogen atom; X represents an oxygen or sulphur atom; n is an integer of from 1 to 2, and/or geometric isomers and/or stereoisomers and/or diastereomers and/or salts and/or hydrates and/or solvates thereof, to the processes for producing the same, to pharmaceutical compositions containing the same and to their use in therapy and/or prevention of a condition which requires modulation of dopamine receptors. |
Application Number
申请号 |
200480021950 |
Application Date
申请日 |
2004.05.21 |
| Title 名称 |
(Thio)carbamoyl-cyclohexane derivatives as D3/D2 receptor antagonists
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Publication Number
公开号 |
1829703 |
Publication Date
公开日 |
2006.09.06 |
| Approval Pub. Date |
|
Granted Pub. Date |
|
| International Classification 分类号 |
C07D243/08,C07D295/12,C07D295/14,C07D401/12,A61K31/495,A61P25/00 |
Applicant(s) Name
申请人 |
Richter Gedeon Vegyeszet |
| Address 地址 |
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| Inventor(s) Name 发明人 |
Againe Csongor Eva, Galambos Janos, Nogradi Katalin, Vago Istvan, Gyertyan Istvan, Kiss Bela, Laszlovszky Istvan, Laszy Judit |
| Attorney & Agent 代理人 |
tang xiaofeng |
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