Sea snail toxin variant polypeptide compound, its preparation process and application thereof

Original document(10 pages) 中文版

The invention discloses a manufacture method for two alpha-whelk toxin variant polypeptide compound, the gene coding the compound and the use of the compound. The polypeptide would be gained through the process of amino acid substitution, decorating, biology filtering, the amino acid sequence from N end to C end is: GCCADPRCNYDHPEIC. It is made by the method of chemical and gene engineering that has activity anti neuron nicotine acetylcholine receptor. It has high value in acceptor search and medicine developing.

Application Number 申请号	200510022672	Application Date 申请日	2005.12.28
Title 名称	Sea snail toxin variant polypeptide compound, its preparation process and application thereof
Publication Number 公开号	1793169	Publication Date 公开日	2006.06.28
Approval Pub. Date		Granted Pub. Date
International Classification 分类号	C07K7/08,C07K4/12,C07K19/00,C12N15/12,C12N15/63,C12N1/21,C12P21/02,C07K1/00,A61P25/04,A61P25/28
Applicant(s) Name 申请人	Nanjing Agriculture Univ.
Address 地址	210095
Inventor(s) Name 发明人	Zhang Zhiguo, Yang Lun, Lian Guifang
Attorney & Agent 代理人	lou gaochao

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