Original document(23 pages) Authorized document(22 pages) 中文版
    1-Oxo-2-(2,6-dioxo-3-fluoropiperidin-3-yl)-isoindolines and 1,3-dioxo-2-(2,6-dioxo-3-fluoropiperidin-3-yl)-isoindolines reduce the levels of inflammatory cytokines such as TNFalpha in a mammal. A typical embodiment is 1,3-dioxo-2- (2,6-dioxo-3-fluoropiperidin-3-yl)-isoindoline.
Application Number
98812419 Application Date
Title 名称 Substituted 2-(2,6-dioxo-3-fluoropiperidin-3-yl)-isoindolines and their use to reduce TNF & alpha levels
Publication Number
1282330 Publication Date
Approval Pub. Date 2006.08.23 Granted Pub. Date 2006.08.23
International Classification 分类号 C07D401/04;A61K31/445
Applicant(s) Name
Celgene Corp.
Address 地址
Inventor(s) Name 发明人 G.W. Muller;D.E. Stirling;R.S. -C. Chen
Attorney & Agent 代理人 xu xun

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