Original document(35 pages)  中文版
    The present invention relates to an improved method for synthesizing nucleosides with a low alpha : beta anomeric ratio. The method comprises coupling a protected furanosyl halide and an appropriately protected heterocycle in the presence of a nucleophilic polar solvent and a strong base.
Application Number
00107145 Application Date
Title 名称 Process for synthesizing nucleotide and the like
Publication Number
1275575 Publication Date
Approval Pub. Date Granted Pub. Date
International Classification 分类号 C07H19/02
Applicant(s) Name
Pfizer Inc.
Address 地址
Inventor(s) Name 发明人 R. W. Scott
Attorney & Agent 代理人 wang jingchao

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