|
Molecular formula : C8H8O3
MW : 152.15
CAS No. :119-36-8
nature : colorless or pale yellow oily liquid with holly leaf flavor. The temperature was -7 -8 ° C, the boiling point of 223.3 ° C and relative density of 1.174, 1.5365 refractive index. Flash point 101.1 ° C Soluble in ethanol, ethyl ether, acetic acid and water-soluble.
Preparation : methyl salicylate widespread in the natural world, is Pyrola grass, small medicated oil when the main ingredients. Also contained in the Tuberose, Jie tree Yilanyilan, cloves, the tea essential oil. Industrial use of salicylic acid and methanol in the presence of sulfuric acid esterification derived. Will acid dissolved in methanol, add sulfate, stirring heated, in response 3h 90-100 ° C, cooling to 30 ° C below, get a reservoir washed with sodium carbonate solution to pH above, and then washed one time. Vacuum distillation, collecting 95-110 ° C (1.33-2.0kPa) distillate, in methyl salicylate. The yield of over 80%. General industrial methyl salicylate content of 99.5%. The consumption of raw materials fixed : Salicylic acid 950kg / t, methanol feeding trial for 47 days / t.
purposes : the goods of similar limited-Pyrola odor, flavor when used as often as a medicine cavity preparation with medicine Paint the Fu Xiang agent, in general flavor, such as trees Jie of blending spices are also applications, such as gum, mouthwash and other population-have used drugs Application. Methyl salicylate is also used as solvents and intermediates for the manufacture of insecticides, fungicides, spices, paints, cosmetics ink and dye fibers such help. Methyl salicylate produced by the reaction of ammonia with salicylaldehyde amide, antipyretic used painkillers salicylaldehyde ethyl amine production, salicylaldehyde amide itself is a kind of antipyretic analgesics. Methyl salicylate by acetylation available acetyl salicylic acid methyl ester (C10H10O4, [580-02-9]). Will methyl salicylate and acetic anhydride 11:50 input, stirring adding sulfuric acid, the reaction temperature not exceeding 60 ° C, about 1 hour, the reaction to complete, will be poured into ice water reaction precipitate crystal, filtering, washing, drying, named acetyl salicylic acid methyl ester. Aspirin by cyclization can be prepared from 4-hydroxy-coumarin. Methyl salicylate as medicine for external application on the line.
Notice:Each item can have many explanations from different angels. If you want grasp the item comprehensively,please see below "more details data". |
Home Products Search Properties Search 中文版