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Molecular formula : no MW : 43000 CAS No. :9001-54-1
nature : yellow crystal. Melting point 172-173 ° C (rapid heating). 1g the 3ml2N materials can be dissolved in acid, 12 ml · hot methanol. Its common hydrochloride (HCL C8H8N4 [304-20-1]. Dihydrazinophthalazine hydrochloride yellow crystal, 273 ° C decomposition. Solubility in water (g/100ml) : 15 ° C, 3.01; 25 ° C, 4.42. In 95% ethanol solubility in 2g/100ml 0, insoluble in ether. pH 2% for the farm.
Preparation : 1-chloro Phthalazoneacetic (see 9720) and by the will of hydrazine 1-chloro Phthalazoneacetic added Hydrazine, in the 87-89 ° C for 12h stirring return, as soon as it is filtered. liquid cooling and crystallization, filtration, in dihydralazine. dihydrazinophthalazine combined with a 15% acid soluble salt, plus alcohol crystallized, available dihydrazinophthalazine hydrochloride.
purposes : for the goods anti-hypertension drug. mouse oral LD50 of 122ml/kg, rat LD50 of 90ml/kg.
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