Molecular formula : C19H20F3NO4
MW : 383.380
CAS No. :69806-50-4
nature : colorless or pale yellow oily liquid. The boiling point of 167 ° C (6.65 × 10-calf), with methanol, C handles, and the Central ethyl ketone, n-hexane, xylene, chloroform immiscible in water solubility of 2ppm.
Preparation : mainly for the following two ways. 1. First ether method by 2-chloro-5-trifluoromethyl - pyridine and hydroquinone in alkaline medium corresponding reaction of the hydroxy ether, and then α-Butyl chloride acid generated from condensation. 2. After the first method ether of hydroquinone and alpha-butyl bromide acid condensation products were derived from the same 2-chloro-5-trichloro - methylpyridine fluoride derived. These two methods need intermediate 2-chloro-5-trifluoromethyl - pyridine, can be 2-chloro-5-trichloro - methylpyridine fluoride derived.
purposes : Wo topiramate fluoride is zoned Ling control grassy weeds and buds after selective herbicide. For cotton, soybean, canola and other field, control annual and perennial weeds, and the results are obvious. Rat oral LD50 of 3000mg/kg, 1490mg/kg male mice and female mice 1770mg/kg.
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